Progesterone Attenuates Hemorrhagic Transformation after Delayed tPA Treatment in an Experimental Mo...
Progesterone Attenuates Hemorrhagic Transformation after Delayed tPA Treatment in an Experimental Model of Stroke in Rats: Involvement of the VEGF–MMP Pathway
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London, England: SAGE Publications
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Language
English
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Publisher
London, England: SAGE Publications
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Contents
Tissue plasminogen activator (tPA) is the only FDA-approved treatment for acute stroke, but its use remains limited. Progesterone (PROG) has shown neuroprotection in ischemia, but before clinical testing, we must determine how it affects hemorrhagic transformation in tPA-treated ischemic rats. Male Sprague–Dawley rats underwent middle cerebral arte...
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Full title
Progesterone Attenuates Hemorrhagic Transformation after Delayed tPA Treatment in an Experimental Model of Stroke in Rats: Involvement of the VEGF–MMP Pathway
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3887344
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3887344
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ISSN
0271-678X
E-ISSN
1559-7016
DOI
10.1038/jcbfm.2013.163
