Active DNA demethylation is required for complete imprint erasure in primordial germ cells
Active DNA demethylation is required for complete imprint erasure in primordial germ cells
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
In mammalian primordial germ cells (PGCs), DNA demethylation is indispensible for parental imprint erasure, which is a reprogramming process essential for normal developmental potential. Thus, it is important to elucidate how DNA demethylation occurs in each imprinted region in PGCs and to determine which DNA demethylation pathway, passive or activ...
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Full title
Active DNA demethylation is required for complete imprint erasure in primordial germ cells
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3888974
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3888974
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep03658
