Epigenetic modulation of the drug resistance genes MGMT, ABCB1 and ABCG2 in glioblastoma multiforme
Epigenetic modulation of the drug resistance genes MGMT, ABCB1 and ABCG2 in glioblastoma multiforme
About this item
Full title
Author / Creator
Oberstadt, Moritz C , Bien-Möller, Sandra , Weitmann, Kerstin , Herzog, Susann , Hentschel, Katharina , Rimmbach, Christian , Vogelgesang, Silke , Balz, Ellen , Fink, Matthias , Michael, Heike , Zeden, Jan-Philip , Bruckmüller, Henrike , Werk, Anneke N , Cascorbi, Ingolf , Hoffmann, Wolfgang , Rosskopf, Dieter , Schroeder, Henry W S and Kroemer, Heyo K
Publisher
England: BioMed Central Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central Ltd
Subjects
More information
Scope and Contents
Contents
Resistance of the highly aggressive glioblastoma multiforme (GBM) to drug therapy is a major clinical problem resulting in a poor patient's prognosis. Beside promoter methylation of the O6-methylguanine-DNA-methyltransferase (MGMT) gene the efflux transporters ABCB1 and ABCG2 have been suggested as pivotal factors contributing to drug resistance, b...
Alternative Titles
Full title
Epigenetic modulation of the drug resistance genes MGMT, ABCB1 and ABCG2 in glioblastoma multiforme
Authors, Artists and Contributors
Author / Creator
Bien-Möller, Sandra
Weitmann, Kerstin
Herzog, Susann
Hentschel, Katharina
Rimmbach, Christian
Vogelgesang, Silke
Balz, Ellen
Fink, Matthias
Michael, Heike
Zeden, Jan-Philip
Bruckmüller, Henrike
Werk, Anneke N
Cascorbi, Ingolf
Hoffmann, Wolfgang
Rosskopf, Dieter
Schroeder, Henry W S
Kroemer, Heyo K
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3890604
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3890604
Other Identifiers
ISSN
1471-2407
E-ISSN
1471-2407
DOI
10.1186/1471-2407-13-617
