Small-Molecule Inhibitors of PKR Improve Glucose Homeostasis in Obese Diabetic Mice
Small-Molecule Inhibitors of PKR Improve Glucose Homeostasis in Obese Diabetic Mice
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Alexandria, VA: American Diabetes Association
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Language
English
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Publisher
Alexandria, VA: American Diabetes Association
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Contents
Obesity and metabolic diseases appear as clusters, often featuring high risk for insulin resistance and type 2 diabetes, and constitute a major global health problem with limited treatment options. Previous studies have shown that double-stranded RNA–dependent kinase, PKR, plays an important role in the nutrient/pathogen-sensing interface, and acts...
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Full title
Small-Molecule Inhibitors of PKR Improve Glucose Homeostasis in Obese Diabetic Mice
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3900541
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3900541
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ISSN
0012-1797,1939-327X
E-ISSN
1939-327X
DOI
10.2337/db13-1019