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Small-Molecule Inhibitors of PKR Improve Glucose Homeostasis in Obese Diabetic Mice

Small-Molecule Inhibitors of PKR Improve Glucose Homeostasis in Obese Diabetic Mice

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3900541

Small-Molecule Inhibitors of PKR Improve Glucose Homeostasis in Obese Diabetic Mice

About this item

Full title

Small-Molecule Inhibitors of PKR Improve Glucose Homeostasis in Obese Diabetic Mice

Publisher

Alexandria, VA: American Diabetes Association

Journal title

Diabetes (New York, N.Y.), 2014-02, Vol.63 (2), p.526-534

Language

English

Formats

Publication information

Publisher

Alexandria, VA: American Diabetes Association

More information

Scope and Contents

Contents

Obesity and metabolic diseases appear as clusters, often featuring high risk for insulin resistance and type 2 diabetes, and constitute a major global health problem with limited treatment options. Previous studies have shown that double-stranded RNA–dependent kinase, PKR, plays an important role in the nutrient/pathogen-sensing interface, and acts...

Alternative Titles

Full title

Small-Molecule Inhibitors of PKR Improve Glucose Homeostasis in Obese Diabetic Mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3900541

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3900541

Other Identifiers

ISSN

0012-1797,1939-327X

E-ISSN

1939-327X

DOI

10.2337/db13-1019

How to access this item