Mycobacterial mistranslation is necessary and sufficient for rifampicin phenotypic resistance
Mycobacterial mistranslation is necessary and sufficient for rifampicin phenotypic resistance
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Errors are inherent in all biological systems. Errors in protein translation are particularly frequent giving rise to a collection of protein quasi-species, the diversity of which will vary according to the error rate. As mistranslation rates rise, these new proteins could produce new phenotypes, although none have been identified to date. Here, we...
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Full title
Mycobacterial mistranslation is necessary and sufficient for rifampicin phenotypic resistance
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3903211
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3903211
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1317580111