TGF-β directs trafficking of the epithelial sodium channel ENaC which has implications for ion and f...
TGF-β directs trafficking of the epithelial sodium channel ENaC which has implications for ion and fluid transport in acute lung injury
About this item
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Author / Creator
Peters, Dorothea M , Vadász, István , Wujak, Lukasz , Wygrecka, Malgorzata , Olschewski, Andrea , Becker, Christin , Herold, Susanne , Papp, Rita , Mayer, Konstantin , Rummel, Sebastian , Brandes, Ralph P , Günther, Andreas , Waldegger, Siegfried , Eickelberg, Oliver , Seeger, Werner and Morty, Rory E
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
TGF-β is a pathogenic factor in patients with acute respiratory distress syndrome (ARDS), a condition characterized by alveolar edema. A unique TGF-β pathway is described, which rapidly promoted internalization of the αβγ epithelial sodium channel (ENaC) complex from the alveolar epithelial cell surface, leading to persistence of pulmonary edema. T...
Alternative Titles
Full title
TGF-β directs trafficking of the epithelial sodium channel ENaC which has implications for ion and fluid transport in acute lung injury
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3903252
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3903252
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1306798111
