High-throughput sequencing of the paired human immunoglobulin heavy and light chain repertoire
High-throughput sequencing of the paired human immunoglobulin heavy and light chain repertoire
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
A new method facilitates high-throughput sequencing of the repertoire of immunoglobulin heavy-light chain pairs in human B cells.
Each B-cell receptor consists of a pair of heavy and light chains. High-throughput sequencing can identify large numbers of heavy- and light-chain variable regions (V
H
and V
L
) in a given B-cell repertoi...
Alternative Titles
Full title
High-throughput sequencing of the paired human immunoglobulin heavy and light chain repertoire
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3910347
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3910347
Other Identifiers
ISSN
1087-0156
E-ISSN
1546-1696
DOI
10.1038/nbt.2492