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High-throughput sequencing of the paired human immunoglobulin heavy and light chain repertoire

High-throughput sequencing of the paired human immunoglobulin heavy and light chain repertoire

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3910347

High-throughput sequencing of the paired human immunoglobulin heavy and light chain repertoire

About this item

Full title

High-throughput sequencing of the paired human immunoglobulin heavy and light chain repertoire

Publisher

New York: Nature Publishing Group US

Journal title

Nature biotechnology, 2013-02, Vol.31 (2), p.166-169

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

A new method facilitates high-throughput sequencing of the repertoire of immunoglobulin heavy-light chain pairs in human B cells.
Each B-cell receptor consists of a pair of heavy and light chains. High-throughput sequencing can identify large numbers of heavy- and light-chain variable regions (V
H
and V
L
) in a given B-cell repertoi...

Alternative Titles

Full title

High-throughput sequencing of the paired human immunoglobulin heavy and light chain repertoire

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3910347

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3910347

Other Identifiers

ISSN

1087-0156

E-ISSN

1546-1696

DOI

10.1038/nbt.2492

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