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MLKL regulates necrotic plasma membrane permeabilization

MLKL regulates necrotic plasma membrane permeabilization

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3915909

MLKL regulates necrotic plasma membrane permeabilization

About this item

Full title

MLKL regulates necrotic plasma membrane permeabilization

Publisher

London: Nature Publishing Group UK

Journal title

Cell research, 2014-02, Vol.24 (2), p.139-140

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Recent data from two independent laboratories have shed new light on the molecular mechanisms by which mixed lineage kinase domainlike (MLKL) promotes a peculiar form of regulated necrosis known as necroptosis. Upon phosphorylation by receptor-interacting protein kinase 3 (RIPK3), MLKL appears indeed to form oligomers that localize to the plasma me...

Alternative Titles

Full title

MLKL regulates necrotic plasma membrane permeabilization

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3915909

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3915909

Other Identifiers

ISSN

1001-0602

E-ISSN

1748-7838

DOI

10.1038/cr.2014.8

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