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Large conserved domains of low DNA methylation maintained by Dnmt3a

Large conserved domains of low DNA methylation maintained by Dnmt3a

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3920905

Large conserved domains of low DNA methylation maintained by Dnmt3a

About this item

Full title

Large conserved domains of low DNA methylation maintained by Dnmt3a

Publisher

New York: Nature Publishing Group US

Journal title

Nature genetics, 2014-01, Vol.46 (1), p.17-23

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Margaret Goodell and colleagues report genome-wide mapping of 5-methylcytosine and 5-hydroxymethylcytosine in purified mouse hematopoietic stem cells. They identify large regions of low methylation with borders marked by 5-hydroxymethylcytosine. These borders become eroded in the absence of DNA methyltransferase 3a.
Gains and losses in DNA methy...

Alternative Titles

Full title

Large conserved domains of low DNA methylation maintained by Dnmt3a

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3920905

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3920905

Other Identifiers

ISSN

1061-4036

E-ISSN

1546-1718

DOI

10.1038/ng.2836

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