SHANK3 overexpression causes manic-like behaviour with unique pharmacogenetic properties
SHANK3 overexpression causes manic-like behaviour with unique pharmacogenetic properties
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Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Mutations in
SHANK3
and large duplications of the region spanning
SHANK3
both cause a spectrum of neuropsychiatric disorders, indicating that proper
SHANK3
dosage is critical for normal brain function. However,
SHANK3
overexpression per se has not been established as a cause of human disorders because 22q13 duplications invo...
Alternative Titles
Full title
SHANK3 overexpression causes manic-like behaviour with unique pharmacogenetic properties
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3923348
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3923348
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature12630
