IRF8 suppresses pathological cardiac remodelling by inhibiting calcineurin signalling
IRF8 suppresses pathological cardiac remodelling by inhibiting calcineurin signalling
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Interferon regulatory factor 8 (IRF8) is known to affect the innate immune response, for example, by regulating the differentiation and function of immune cells. However, whether IRF8 can influence cardiac hypertrophy is unknown. Here we show that IRF8 levels are decreased in human dilated/hypertrophic cardiomyopathic hearts and in murine hypertrop...
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Full title
IRF8 suppresses pathological cardiac remodelling by inhibiting calcineurin signalling
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3929801
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3929801
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms4303
