MiRNA-210 modulates a nickel-induced cellular energy metabolism shift by repressing the iron–sulfur...
MiRNA-210 modulates a nickel-induced cellular energy metabolism shift by repressing the iron–sulfur cluster assembly proteins ISCU1/2 in Neuro-2a cells
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
The cellular energy metabolism shift, characterized by the inhibition of oxidative phosphorylation (OXPHOS) and enhancement of glycolysis, is involved in nickel-induced neurotoxicity. MicroRNA-210 (miR-210) is regulated by hypoxia-inducible transcription factor-1
α
(HIF-1
α
) under hypoxic conditions and controls mitochondrial energy me...
Alternative Titles
Full title
MiRNA-210 modulates a nickel-induced cellular energy metabolism shift by repressing the iron–sulfur cluster assembly proteins ISCU1/2 in Neuro-2a cells
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3944272
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3944272
Other Identifiers
ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/cddis.2014.60
