Erythropoietin Inhibits HIF-1α Expression via Upregulation of PHD-2 Transcription and Translation in...
Erythropoietin Inhibits HIF-1α Expression via Upregulation of PHD-2 Transcription and Translation in an In Vitro Model of Hypoxia–Ischemia
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Publisher
Boston: Springer US
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Language
English
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Boston: Springer US
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Contents
Hypoxia inducible factor (HIF)-1α is the central transcriptional factor for the regulation of oxygen-associated genes in response to hypoxia. Erythropoietin (EPO), a hematopoietic growth factor, increases oxygen availability during hypoxia/ischemia and is associated with neuroprotection following hypoxia–ischemia in laboratory models of stroke. How...
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Full title
Erythropoietin Inhibits HIF-1α Expression via Upregulation of PHD-2 Transcription and Translation in an In Vitro Model of Hypoxia–Ischemia
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3946340
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3946340
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ISSN
1868-4483
E-ISSN
1868-601X
DOI
10.1007/s12975-013-0312-z
