Soybean greatly reduces valproic acid plasma concentrations: A food–drug interaction study
Soybean greatly reduces valproic acid plasma concentrations: A food–drug interaction study
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
The aim of this study was to investigate the effects of soy on the pharmacokinetics and pharmacodynamics of valproic acid (VPA). In a preclinical study, rats were pretreated with two different amounts of soy extract for five days (150 mg/kg and 500 mg/kg), which resulted in decreases of 57% and 65% in the C
max
of VPA, respectively. AUC of VP...
Alternative Titles
Full title
Soybean greatly reduces valproic acid plasma concentrations: A food–drug interaction study
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3950581
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3950581
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep04362
