The smallest stroke: occlusion of one penetrating vessel leads to infarction and a cognitive deficit
The smallest stroke: occlusion of one penetrating vessel leads to infarction and a cognitive deficit
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
The authors utilize optical occlusion of penetrating blood vessels to induce cortical microinfarcts. Occlusion of even a single such vessel leads to behavioral dysfunction, whereas multiple, yet sparse, occlusions can induce substantial tissue damage. Excitotoxicity blockers ameliorate both effects.
Microinfarctions are present in the aged and i...
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Full title
The smallest stroke: occlusion of one penetrating vessel leads to infarction and a cognitive deficit
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3952571
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3952571
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ISSN
1097-6256
E-ISSN
1546-1726
DOI
10.1038/nn.3278
