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Real-Time Evaluation of Myosin Light Chain Kinase Activation in Smooth Muscle Tissues from a Transge...

Real-Time Evaluation of Myosin Light Chain Kinase Activation in Smooth Muscle Tissues from a Transge...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_395960

Real-Time Evaluation of Myosin Light Chain Kinase Activation in Smooth Muscle Tissues from a Transgenic Calmodulin-Biosensor Mouse

About this item

Full title

Real-Time Evaluation of Myosin Light Chain Kinase Activation in Smooth Muscle Tissues from a Transgenic Calmodulin-Biosensor Mouse

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2004-04, Vol.101 (16), p.6279-6284

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Ca2+/calmodulin (CaM)-dependent phosphorylation of myosin regulatory light chain (RLC) by myosin light chain kinase (MLCK) initiates smooth muscle contraction and regulates actomyosin-based cytoskeletal functions in nonmuscle cells. The net extent of RLC phosphorylation is controlled by MLCK activity relative to myosin light chain phosphatase activ...

Alternative Titles

Full title

Real-Time Evaluation of Myosin Light Chain Kinase Activation in Smooth Muscle Tissues from a Transgenic Calmodulin-Biosensor Mouse

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_395960

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_395960

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0308742101

How to access this item