Real-Time Evaluation of Myosin Light Chain Kinase Activation in Smooth Muscle Tissues from a Transge...
Real-Time Evaluation of Myosin Light Chain Kinase Activation in Smooth Muscle Tissues from a Transgenic Calmodulin-Biosensor Mouse
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Ca2+/calmodulin (CaM)-dependent phosphorylation of myosin regulatory light chain (RLC) by myosin light chain kinase (MLCK) initiates smooth muscle contraction and regulates actomyosin-based cytoskeletal functions in nonmuscle cells. The net extent of RLC phosphorylation is controlled by MLCK activity relative to myosin light chain phosphatase activ...
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Full title
Real-Time Evaluation of Myosin Light Chain Kinase Activation in Smooth Muscle Tissues from a Transgenic Calmodulin-Biosensor Mouse
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_395960
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_395960
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0308742101