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Chemotherapy-induced bone marrow nerve injury impairs hematopoietic regeneration

Chemotherapy-induced bone marrow nerve injury impairs hematopoietic regeneration

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3964478

Chemotherapy-induced bone marrow nerve injury impairs hematopoietic regeneration

About this item

Full title

Chemotherapy-induced bone marrow nerve injury impairs hematopoietic regeneration

Publisher

New York: Nature Publishing Group US

Journal title

Nature medicine, 2013-06, Vol.19 (6), p.695-703

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Many chemotherapy drugs cause sensory nerve damage as well as long-lasting damage to hematopoietic regeneration in the bone marrow. Paul Frenette and his colleagues show that this hematopoietic damage is caused by injury to bone marrow sympathetic nerve fibers, disrupting the hematopoietic stem cell niche. These findings point to the potential of n...

Alternative Titles

Full title

Chemotherapy-induced bone marrow nerve injury impairs hematopoietic regeneration

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3964478

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3964478

Other Identifiers

ISSN

1078-8956

E-ISSN

1546-170X

DOI

10.1038/nm.3155

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