Astrocytes mediate synapse elimination through MEGF10 and MERTK pathways
Astrocytes mediate synapse elimination through MEGF10 and MERTK pathways
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London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
To achieve its precise neural connectivity, the developing mammalian nervous system undergoes extensive activity-dependent synapse remodelling. Recently, microglial cells have been shown to be responsible for a portion of synaptic pruning, but the remaining mechanisms remain unknown. Here we report a new role for astrocytes in actively engulfing ce...
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Full title
Astrocytes mediate synapse elimination through MEGF10 and MERTK pathways
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3969024
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3969024
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature12776
