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Constitutional and somatic rearrangement of chromosome 21 in acute lymphoblastic leukaemia

Constitutional and somatic rearrangement of chromosome 21 in acute lymphoblastic leukaemia

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3976272

Constitutional and somatic rearrangement of chromosome 21 in acute lymphoblastic leukaemia

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

A rare constitutional translocation between chromosomes 15 and 21 predisposes to catastrophic chromosomal damage followed by amplification of megabase regions, causing a specific subtype of acute lymphoblastic leukaemia.
Chromothripsis in acute lymphoblastic leukaemia
A subgroup comprising some 2% of patients with the childhood cancer acute l...

Alternative Titles

Full title

Constitutional and somatic rearrangement of chromosome 21 in acute lymphoblastic leukaemia

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3976272

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3976272

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature13115

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