Constitutional and somatic rearrangement of chromosome 21 in acute lymphoblastic leukaemia
Constitutional and somatic rearrangement of chromosome 21 in acute lymphoblastic leukaemia
About this item
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Author / Creator
Li, Yilong , Schwab, Claire , Ryan, Sarra L. , Papaemmanuil, Elli , Robinson, Hazel M. , Jacobs, Patricia , Moorman, Anthony V. , Dyer, Sara , Borrow, Julian , Griffiths, Mike , Heerema, Nyla A. , Carroll, Andrew J. , Talley, Polly , Bown, Nick , Telford, Nick , Ross, Fiona M. , Gaunt, Lorraine , McNally, Richard J. Q. , Young, Bryan D. , Sinclair, Paul , Rand, Vikki , Teixeira, Manuel R. , Joseph, Olivia , Robinson, Ben , Maddison, Mark , Dastugue, Nicole , Vandenberghe, Peter , Haferlach, Claudia , Stephens, Philip J. , Cheng, Jiqiu , Van Loo, Peter , Stratton, Michael R. , Campbell, Peter J. and Harrison, Christine J.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
A rare constitutional translocation between chromosomes 15 and 21 predisposes to catastrophic chromosomal damage followed by amplification of megabase regions, causing a specific subtype of acute lymphoblastic leukaemia.
Chromothripsis in acute lymphoblastic leukaemia
A subgroup comprising some 2% of patients with the childhood cancer acute l...
Alternative Titles
Full title
Constitutional and somatic rearrangement of chromosome 21 in acute lymphoblastic leukaemia
Authors, Artists and Contributors
Author / Creator
Schwab, Claire
Ryan, Sarra L.
Papaemmanuil, Elli
Robinson, Hazel M.
Jacobs, Patricia
Moorman, Anthony V.
Dyer, Sara
Borrow, Julian
Griffiths, Mike
Heerema, Nyla A.
Carroll, Andrew J.
Talley, Polly
Bown, Nick
Telford, Nick
Ross, Fiona M.
Gaunt, Lorraine
McNally, Richard J. Q.
Young, Bryan D.
Sinclair, Paul
Rand, Vikki
Teixeira, Manuel R.
Joseph, Olivia
Robinson, Ben
Maddison, Mark
Dastugue, Nicole
Vandenberghe, Peter
Haferlach, Claudia
Stephens, Philip J.
Cheng, Jiqiu
Van Loo, Peter
Stratton, Michael R.
Campbell, Peter J.
Harrison, Christine J.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3976272
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3976272
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature13115