Immunosuppressive CD71+ erythroid cells compromise neonatal host defence against infection
Immunosuppressive CD71+ erythroid cells compromise neonatal host defence against infection
About this item
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Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
In neonatal mice, susceptibility to infection is due to an enriched subset of arginase-2-expressing CD71
+
erythroid cells, which suppresses the systemic activation of immune cells, thereby protecting neonates against aberrant inflammation triggered by colonization with commensal microbes.
Explaining newborns' vulnerability to infection
Alternative Titles
Full title
Immunosuppressive CD71+ erythroid cells compromise neonatal host defence against infection
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3979598
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3979598
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature12675
