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Sulforaphane synergistically enhances the cytotoxicity of arsenic trioxide in multiple myeloma cells...

Sulforaphane synergistically enhances the cytotoxicity of arsenic trioxide in multiple myeloma cells...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3981004

Sulforaphane synergistically enhances the cytotoxicity of arsenic trioxide in multiple myeloma cells via stress-mediated pathways

About this item

Full title

Sulforaphane synergistically enhances the cytotoxicity of arsenic trioxide in multiple myeloma cells via stress-mediated pathways

Publisher

Athens: D.A. Spandidos

Journal title

Oncology reports, 2012-11, Vol.28 (5), p.1851-1858

Language

English

Formats

Publication information

Publisher

Athens: D.A. Spandidos

More information

Scope and Contents

Contents

Persistent paraprotein production in plasma cells necessitates a highly developed rough endoplasmic reticulum (ER) that is unusually susceptible to perturbations in protein synthesis. This biology is believed to account for the exquisite sensitivity of multiple myeloma (MM) to the proteasomal inhibitor bortezomib (BTZ). Despite remarkable response...

Alternative Titles

Full title

Sulforaphane synergistically enhances the cytotoxicity of arsenic trioxide in multiple myeloma cells via stress-mediated pathways

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3981004

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3981004

Other Identifiers

ISSN

1021-335X

E-ISSN

1791-2431

DOI

10.3892/or.2012.1977

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