TGF-β autocrine pathway and MAPK signaling promote cell invasiveness and in vivo mammary adenocarcin...
TGF-β autocrine pathway and MAPK signaling promote cell invasiveness and in vivo mammary adenocarcinoma tumor progression
About this item
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Author / Creator
Publisher
Athens: D.A. Spandidos
Journal title
Language
English
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Publication information
Publisher
Athens: D.A. Spandidos
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Scope and Contents
Contents
Breast cancer progression and metastasis have been linked to abnormal signaling by transforming growth factor-β (TGF-β) cytokines. In early-stage breast cancers, TGF-β exhibits tumor suppressor activity by repressing cell proliferation and inducing cell death, whereas in advanced-stage tumors, TGF-β promotes invasion and metastatic dissemination. T...
Alternative Titles
Full title
TGF-β autocrine pathway and MAPK signaling promote cell invasiveness and in vivo mammary adenocarcinoma tumor progression
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3981025
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3981025
Other Identifiers
ISSN
1021-335X,1791-2431
E-ISSN
1791-2431
DOI
10.3892/or.2012.1813
