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Structural Stereochemistry of Androstene Hormones Determines Interactions with Human Androgen, Estro...

Structural Stereochemistry of Androstene Hormones Determines Interactions with Human Androgen, Estro...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3981456

Structural Stereochemistry of Androstene Hormones Determines Interactions with Human Androgen, Estrogen, and Glucocorticoid Receptors

About this item

Full title

Structural Stereochemistry of Androstene Hormones Determines Interactions with Human Androgen, Estrogen, and Glucocorticoid Receptors

Publisher

Cairo, Egypt: Hindawi Puplishing Corporation

Journal title

International Journal of Medicinal Chemistry (Online), 2013-01, Vol.2013 (2013), p.1-8

Language

English

Formats

Publication information

Publisher

Cairo, Egypt: Hindawi Puplishing Corporation

More information

Scope and Contents

Contents

DHEA, 17α-AED, 17β-AED, and 17β-AET exhibit strong biological activity that has been attributed to androgenic, estrogenic, or antiglucocorticoid activity in vivo and in vitro. This study compared DHEA, 17α-AED, 17β-AED, and 17β-AET for their ability to activate the human AR, ER, and GR and determine the relative androgenicity, estrogenicity, and gl...

Alternative Titles

Full title

Structural Stereochemistry of Androstene Hormones Determines Interactions with Human Androgen, Estrogen, and Glucocorticoid Receptors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3981456

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3981456

Other Identifiers

ISSN

2090-2069

E-ISSN

2090-2077

DOI

10.1155/2013/203606

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