Activation of the mitochondrial unfolded protein response does not predict longevity in Caenorhabdit...
Activation of the mitochondrial unfolded protein response does not predict longevity in Caenorhabditis elegans
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
Recent studies have propagated the model that the mitochondrial unfolded protein response (UPR
mt
) is causal for lifespan extension from inhibition of the electron transport chain (ETC) in
Caenorhabditis elegans
. Here we report a genome-wide RNAi screen for negative regulators of the UPR
mt
. Lifespan analysis of nineteen RNAi c...
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Full title
Activation of the mitochondrial unfolded protein response does not predict longevity in Caenorhabditis elegans
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3984390
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3984390
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms4483
