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Measuring Chromatin Interaction Dynamics on the Second Time Scale at Single-Copy Genes

Measuring Chromatin Interaction Dynamics on the Second Time Scale at Single-Copy Genes

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3997053

Measuring Chromatin Interaction Dynamics on the Second Time Scale at Single-Copy Genes

About this item

Full title

Measuring Chromatin Interaction Dynamics on the Second Time Scale at Single-Copy Genes

Publisher

United States: American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2013-10, Vol.342 (6156), p.369-372

Language

English

Formats

Publication information

Publisher

United States: American Association for the Advancement of Science

More information

Scope and Contents

Contents

The chromatin immunoprecipitation (ChIP) assay is widely used to capture interactions between chromatin and regulatory proteins, but it is unknown how stable most native interactions are. Although live-cell imaging suggests short-lived interactions at tandem gene arrays, current methods cannot measure rapid binding dynamics at single-copy genes. We...

Alternative Titles

Full title

Measuring Chromatin Interaction Dynamics on the Second Time Scale at Single-Copy Genes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3997053

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3997053

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.1242369

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