Desmoglein-1 regulates esophageal epithelial barrier function and immune responses in eosinophilic e...
Desmoglein-1 regulates esophageal epithelial barrier function and immune responses in eosinophilic esophagitis
About this item
Full title
Author / Creator
Sherrill, J D , KC, K , Wu, D , Djukic, Z , Caldwell, J M , Stucke, E M , Kemme, K A , Costello, M S , Mingler, M K , Blanchard, C , Collins, M H , Abonia, J P , Putnam, P E , Dellon, E S , Orlando, R C , Hogan, S P and Rothenberg, M E
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publication information
Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
The desmosomal cadherin desmoglein-1 (DSG1) is an essential intercellular adhesion molecule that is altered in various human cutaneous disorders; however, its regulation and function in allergic disease remains unexplored. Herein, we demonstrate a specific reduction in DSG1 in esophageal biopsies from patients with eosinophilic esophagitis (EoE), a...
Alternative Titles
Full title
Desmoglein-1 regulates esophageal epithelial barrier function and immune responses in eosinophilic esophagitis
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3999291
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3999291
Other Identifiers
ISSN
1933-0219
E-ISSN
1935-3456
DOI
10.1038/mi.2013.90
