Brain galanin system genes interact with life stresses in depression-related phenotypes
Brain galanin system genes interact with life stresses in depression-related phenotypes
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Galanin is a stress-inducible neuropeptide and cotransmitter in serotonin and norepinephrine neurons with a possible role in stress-related disorders. Here we report that variants in genes for galanin (GAL) and its receptors (GALR1, GALR2, GALR3), despite their disparate genomic loci, conferred increased risk of depression and anxiety in people who...
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Full title
Brain galanin system genes interact with life stresses in depression-related phenotypes
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4000859
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4000859
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1403649111
