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Methyltransferase G9A regulates T cell differentiation during murine intestinal inflammation

Methyltransferase G9A regulates T cell differentiation during murine intestinal inflammation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4001530

Methyltransferase G9A regulates T cell differentiation during murine intestinal inflammation

About this item

Full title

Methyltransferase G9A regulates T cell differentiation during murine intestinal inflammation

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2014-05, Vol.124 (5), p.1945-1955

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

Inflammatory bowel disease (IBD) pathogenesis is associated with dysregulated CD4⁺ Th cell responses, with intestinal homeostasis depending on the balance between IL-17-producing Th17 and Foxp3⁺ Tregs. Differentiation of naive T cells into Th17 and Treg subsets is associated with specific gene expression profiles; however, the contribution of epige...

Alternative Titles

Full title

Methyltransferase G9A regulates T cell differentiation during murine intestinal inflammation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4001530

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4001530

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI69592

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