CXCL11-dependent induction of FOXP3-negative regulatory T cells suppresses autoimmune encephalomyeli...
CXCL11-dependent induction of FOXP3-negative regulatory T cells suppresses autoimmune encephalomyelitis
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United States: American Society for Clinical Investigation
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Language
English
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United States: American Society for Clinical Investigation
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Contents
A single G protein-coupled receptor (GPCR) can activate multiple signaling cascades based on the binding of different ligands. The biological relevance of this feature in immune regulation has not been evaluated. The chemokine-binding GPCR CXCR3 is preferentially expressed on CD4+ T cells, and canonically binds 3 structurally related chemokines: CX...
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Full title
CXCL11-dependent induction of FOXP3-negative regulatory T cells suppresses autoimmune encephalomyelitis
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4001543
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4001543
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ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI71951