Over-production of nitric oxide by oxidative stress- induced activation of the TGF-β1/PI3K/Akt pathw...
Over-production of nitric oxide by oxidative stress- induced activation of the TGF-β1/PI3K/Akt pathway in mesangial cells cultured in high glucose
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Author / Creator
Zhai, Yun-peng , Lu, Qian , Liu, Yao-wu , Cheng, Qian , Wei, Ya-qin , Zhang, Fan , Li, Cheng-lin and Yin, Xiao-xing
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Contents
Aim： To investigate whether NO over-production in rat mesangial cells cultured in high glucose （HG） is related to activation of the TG F-β1/PI3 K/Akt pathway. Methods： Rat mesangial cells line （HBZY-1） was exposed to HG （24.44 mmol/L） or H2O2 （10 pmol/L） for 16 h. NO release was quantified using the Griess assay. The TGF-β1 level was measured using...
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Full title
Over-production of nitric oxide by oxidative stress- induced activation of the TGF-β1/PI3K/Akt pathway in mesangial cells cultured in high glucose
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4002794
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4002794
Other Identifiers
ISSN
1671-4083
E-ISSN
1745-7254
DOI
10.1038/aps.2012.207
