Simvastatin suppresses vascular inflammation and atherosclerosis in ApoE-/- mice by downregulating t...
Simvastatin suppresses vascular inflammation and atherosclerosis in ApoE-/- mice by downregulating the HMGB1-RAGE axis
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Author / Creator
Liu, Ming , Yu, Ying , Jiang, Hong , Zhang, Lei , Zhang, Pei-pei , Yu, Peng , Jia, Jian-guo , Chen, Rui-zhen , Zou, Yun-zeng and Ge, Jun-bo
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Aim： High mobility group box protein 1 （HMGB1） and receptor for the advanced glycation end product （RAGE） play pivotal roles in vascular inflammation and atherosclerosis. The aim of this study was to determine whether the HMGB1-RAGE axis was involved in the actions of simvastatin on vascular inflammation and atherosclerosis in ApoE-/- mice. Methods...
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Full title
Simvastatin suppresses vascular inflammation and atherosclerosis in ApoE-/- mice by downregulating the HMGB1-RAGE axis
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4002903
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4002903
Other Identifiers
ISSN
1671-4083
E-ISSN
1745-7254
DOI
10.1038/aps.2013.8
