IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics
IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics
About this item
Full title
Author / Creator
Sasaki, Masato , Knobbe, Christiane B. , Munger, Joshua C. , Lind, Evan F. , Brenner, Dirk , Brüstle, Anne , Harris, Isaac S. , Holmes, Roxanne , Wakeham, Andrew , Haight, Jillian , You-Ten, Annick , Li, Wanda Y. , Schalm, Stefanie , Su, Shinsan M. , Virtanen, Carl , Reifenberger, Guido , Ohashi, Pamela S. , Barber, Dwayne L. , Figueroa, Maria E. , Melnick, Ari , Zúñiga-Pflücker, Juan-Carlos and Mak, Tak W.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Mutations in isocitrate dehydrogenases IDH1 and IDH2 are common in human gliomas and acute myeloid leukaemias; here, mice that carry the IDH1(R132H) mutation are described, in a new model that should help in investigating the links between mutant IDH1 and leukaemia.
An
IDH1
–mutant-mouse leukaemia model
Mutations in the
IDH1
and
Alternative Titles
Full title
IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics
Authors, Artists and Contributors
Author / Creator
Knobbe, Christiane B.
Munger, Joshua C.
Lind, Evan F.
Brenner, Dirk
Brüstle, Anne
Harris, Isaac S.
Holmes, Roxanne
Wakeham, Andrew
Haight, Jillian
You-Ten, Annick
Li, Wanda Y.
Schalm, Stefanie
Su, Shinsan M.
Virtanen, Carl
Reifenberger, Guido
Ohashi, Pamela S.
Barber, Dwayne L.
Figueroa, Maria E.
Melnick, Ari
Zúñiga-Pflücker, Juan-Carlos
Mak, Tak W.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4005896
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4005896
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature11323
