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Activating ESR1 mutations in hormone-resistant metastatic breast cancer

Activating ESR1 mutations in hormone-resistant metastatic breast cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4009946

Activating ESR1 mutations in hormone-resistant metastatic breast cancer

About this item

Full title

Activating ESR1 mutations in hormone-resistant metastatic breast cancer

Publisher

New York: Nature Publishing Group US

Journal title

Nature genetics, 2013-12, Vol.45 (12), p.1446-1451

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Arul Chinnaiyan and colleagues report the results of prospective clinical sequencing of 11 estrogen receptor–positive metastatic breast cancers. They identify
ESR1
mutations affecting the ligand-binding domain in six hormone-resistant metastatic breast cancers and show that the mutant estrogen receptors are constitutively active and continue...

Alternative Titles

Full title

Activating ESR1 mutations in hormone-resistant metastatic breast cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4009946

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4009946

Other Identifiers

ISSN

1061-4036

E-ISSN

1546-1718

DOI

10.1038/ng.2823

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