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A 3′UTR polymorphism modulates mRNA stability of the oncogene and drug target Polo-like Kinase 1

A 3′UTR polymorphism modulates mRNA stability of the oncogene and drug target Polo-like Kinase 1

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4020576

A 3′UTR polymorphism modulates mRNA stability of the oncogene and drug target Polo-like Kinase 1

About this item

Full title

A 3′UTR polymorphism modulates mRNA stability of the oncogene and drug target Polo-like Kinase 1

Publisher

London: BioMed Central

Journal title

Molecular cancer, 2014-04, Vol.13 (1), p.87-87, Article 87

Language

English

Formats

Publication information

Publisher

London: BioMed Central

More information

Scope and Contents

Contents

Doc number: 87 Abstract Background: The Polo-like Kinase 1 (PLK1) protein regulates cell cycle progression and is overexpressed in many malignant tissues. Overexpression is associated with poor prognosis in several cancer entities, whereby expression of PLK1 shows high inter-individual variability. Although PLK1 is extensively studied, not much is...

Alternative Titles

Full title

A 3′UTR polymorphism modulates mRNA stability of the oncogene and drug target Polo-like Kinase 1

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4020576

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4020576

Other Identifiers

ISSN

1476-4598

E-ISSN

1476-4598

DOI

10.1186/1476-4598-13-87

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