Effect of blood brain barrier permeability in recurrent high grade gliomas on the intratumoral pharm...
Effect of blood brain barrier permeability in recurrent high grade gliomas on the intratumoral pharmacokinetics of methotrexate: a microdialysis study
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Publisher
Boston: Springer US
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English
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Publisher
Boston: Springer US
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Purpose
: Determining whether potentially therapeutic drug exposure is achieved within brain tumors in an exploratory clinical investigation would provide a rational basis for selecting agents for evaluation in phase II trials. This study investigated the use of microdialysis to assess intratumoral drug distribution in patients with recurrent hi...
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Full title
Effect of blood brain barrier permeability in recurrent high grade gliomas on the intratumoral pharmacokinetics of methotrexate: a microdialysis study
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4029102
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4029102
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ISSN
0167-594X
E-ISSN
1573-7373
DOI
10.1007/s11060-008-9678-2