Pathogenic potential of interferon αβ in acute influenza infection
Pathogenic potential of interferon αβ in acute influenza infection
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Influenza symptoms vary from mild disease to death; however, determinants of severity are unclear. Type I interferons (IFNαβ) are recognized as key antiviral cytokines. Here we show that, surprisingly, influenza-infected 129 mice have increased lung damage, morbidity and mortality, yet higher levels of IFNαβ, than C57BL/6 mice. Consistently, IFNα t...
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Full title
Pathogenic potential of interferon αβ in acute influenza infection
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4033792
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4033792
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms4864
