Altered proteome turnover and remodeling by short‐term caloric restriction or rapamycin rejuvenate t...
Altered proteome turnover and remodeling by short‐term caloric restriction or rapamycin rejuvenate the aging heart
About this item
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Author / Creator
Publisher
England: John Wiley & Sons, Inc
Journal title
Language
English
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Publisher
England: John Wiley & Sons, Inc
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Summary
Chronic caloric restriction (CR) and rapamycin inhibit the mechanistic target of rapamycin (mTOR) signaling, thereby regulating metabolism and suppressing protein synthesis. Caloric restriction or rapamycin extends murine lifespan and ameliorates many aging‐associated disorders; however, the beneficial effects of shorter treatment on car...
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Full title
Altered proteome turnover and remodeling by short‐term caloric restriction or rapamycin rejuvenate the aging heart
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4040127
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4040127
Other Identifiers
ISSN
1474-9718
E-ISSN
1474-9726
DOI
10.1111/acel.12203
