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Modulation of the human ρ1 GABAA receptor by inhibitory steroids

Modulation of the human ρ1 GABAA receptor by inhibitory steroids

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4048647

Modulation of the human ρ1 GABAA receptor by inhibitory steroids

About this item

Full title

Modulation of the human ρ1 GABAA receptor by inhibitory steroids

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Psychopharmacology, 2014-09, Vol.231 (17), p.3467-3478

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Rationale
Modulators of the ρ1 GABA
A
receptor may be useful in the treatment of visual, sleep, and cognitive disorders. Neuroactive steroids and analogues have been shown to modulate ρ1 receptor function, but the molecular mechanisms are poorly understood.
Objectives
We employed electrophysiology and voltage-clamp fluorometry to com...

Alternative Titles

Full title

Modulation of the human ρ1 GABAA receptor by inhibitory steroids

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4048647

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4048647

Other Identifiers

ISSN

0033-3158

E-ISSN

1432-2072

DOI

10.1007/s00213-013-3379-z

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