PADI4 acts as a coactivator of Tal1 by counteracting repressive histone arginine methylation
PADI4 acts as a coactivator of Tal1 by counteracting repressive histone arginine methylation
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Contents
The transcription factor Tal1 is a critical activator or repressor of gene expression in hematopoiesis and leukaemia. The mechanism by which Tal1 differentially influences transcription of distinct genes is not fully understood. Here we show that Tal1 interacts with the peptidylarginine deiminase IV (PADI4). We demonstrate that PADI4 can act as an...
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PADI4 acts as a coactivator of Tal1 by counteracting repressive histone arginine methylation
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4050257
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4050257
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms4995
