Analyses of clinicopathological, molecular, and prognostic associations of KRAS codon 61 and codon 1...
Analyses of clinicopathological, molecular, and prognostic associations of KRAS codon 61 and codon 146 mutations in colorectal cancer: cohort study and literature review
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Author / Creator
Imamura, Yu , Lochhead, Paul , Yamauchi, Mai , Kuchiba, Aya , Qian, Zhi Rong , Liao, Xiaoyun , Nishihara, Reiko , Jung, Seungyoun , Wu, Kana , Nosho, Katsuhiko , Wang, Yaoyu E , Peng, Shouyong , Bass, Adam J , Haigis, Kevin M , Meyerhardt, Jeffrey A , Chan, Andrew T , Fuchs, Charles S and Ogino, Shuji
Publisher
England: BioMed Central Ltd
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English
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Publisher
England: BioMed Central Ltd
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Contents
KRAS mutations in codons 12 and 13 are established predictive biomarkers for anti-EGFR therapy in colorectal cancer. Previous studies suggest that KRAS codon 61 and 146 mutations may also predict resistance to anti-EGFR therapy in colorectal cancer. However, clinicopathological, molecular, and prognostic features of colorectal carcinoma with KRAS c...
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Full title
Analyses of clinicopathological, molecular, and prognostic associations of KRAS codon 61 and codon 146 mutations in colorectal cancer: cohort study and literature review
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4051153
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4051153
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ISSN
1476-4598
E-ISSN
1476-4598
DOI
10.1186/1476-4598-13-135
