Developmental cues for the maturation of metabolic, electrophysiological and calcium handling proper...
Developmental cues for the maturation of metabolic, electrophysiological and calcium handling properties of human pluripotent stem cell-derived cardiomyocytes
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Publisher
England: BioMed Central Ltd
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Language
English
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England: BioMed Central Ltd
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Scope and Contents
Contents
Human pluripotent stem cells (hPSCs), including embryonic and induced pluripotent stem cells, are abundant sources of cardiomyocytes (CMs) for cell replacement therapy and other applications such as disease modeling, drug discovery and cardiotoxicity screening. However, hPSC-derived CMs display immature structural, electrophysiological, calcium-han...
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Developmental cues for the maturation of metabolic, electrophysiological and calcium handling properties of human pluripotent stem cell-derived cardiomyocytes
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4055054
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4055054
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ISSN
1757-6512
E-ISSN
1757-6512
DOI
10.1186/scrt406