Endothelin-1 induces a glycolytic switch in pulmonary arterial endothelial cells via the mitochondri...
Endothelin-1 induces a glycolytic switch in pulmonary arterial endothelial cells via the mitochondrial translocation of endothelial nitric oxide synthase
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United States: American Thoracic Society
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Language
English
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United States: American Thoracic Society
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Contents
Recent studies have indicated that, during the development of pulmonary hypertension (PH), there is a switch from oxidative phosphorylation to glycolysis in the pulmonary endothelium. However, the mechanisms underlying this phenomenon have not been elucidated. Endothelin (ET)-1, an endothelial-derived vasoconstrictor peptide, is increased in PH, an...
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Full title
Endothelin-1 induces a glycolytic switch in pulmonary arterial endothelial cells via the mitochondrial translocation of endothelial nitric oxide synthase
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4068912
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4068912
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ISSN
1044-1549
E-ISSN
1535-4989
DOI
10.1165/rcmb.2013-0187OC