Real-time imaging of oxidative and nitrosative stress in the liver of live animals for drug-toxicity...
Real-time imaging of oxidative and nitrosative stress in the liver of live animals for drug-toxicity testing
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Semiconducting polymer nanoparticles are used to image toxic reactive oxygen and reactive nitrogen species in live mice.
Current drug-safety assays for hepatotoxicity rely on biomarkers with low predictive power. The production of radical species, specifically reactive oxygen species (ROS) and reactive nitrogen species (RNS), has been proposed a...
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Full title
Real-time imaging of oxidative and nitrosative stress in the liver of live animals for drug-toxicity testing
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4070437
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4070437
Other Identifiers
ISSN
1087-0156
E-ISSN
1546-1696
DOI
10.1038/nbt.2838
