Survivin family proteins as novel molecular determinants of doxorubicin resistance in organotypic hu...
Survivin family proteins as novel molecular determinants of doxorubicin resistance in organotypic human breast tumors
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
The molecular determinants of breast cancer resistance to first-line anthracycline-containing chemotherapy are unknown.
We examined the response to doxorubicin of organotypic cultures of primary human breast tumors ex vivo with respect to cell proliferation, DNA damage and modulation of apoptosis. Samples were analyzed for genome-wide modulation...
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Survivin family proteins as novel molecular determinants of doxorubicin resistance in organotypic human breast tumors
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4076638
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4076638
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ISSN
1465-542X,1465-5411
E-ISSN
1465-542X
DOI
10.1186/bcr3666
