Analysis of single-nucleotide polymorphisms (SNPs) in human CYP3A4 and CYP3A5 genes: potential impli...
Analysis of single-nucleotide polymorphisms (SNPs) in human CYP3A4 and CYP3A5 genes: potential implications for the metabolism of HIV drugs
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Publisher
England: Springer Science and Business Media LLC
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Language
English
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England: Springer Science and Business Media LLC
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Contents
Drug metabolism via the cytochrome P450 (CYP450) system has emerged as an important determinant in the occurrence of several drug interactions (adverse drug reactions, reduced pharmacological effect, drug toxicities). In particular, CYP3A4 and CYP3A5 (interacting with more than 60% of licensed drugs) exhibit the most individual variations of gene e...
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Full title
Analysis of single-nucleotide polymorphisms (SNPs) in human CYP3A4 and CYP3A5 genes: potential implications for the metabolism of HIV drugs
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4083125
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4083125
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ISSN
1471-2350,1471-2156
E-ISSN
1471-2350,1471-2156
DOI
10.1186/1471-2350-15-76
