Regulation of type I interferon responses
Regulation of type I interferon responses
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Key Points
Type I interferon (IFN) responses are regulated by host, pathogen and environmental factors. These factors calibrate the host defences while limiting tissue damage and preventing autoimmunity.
Type I IFNs signal via the IFNα receptor (IFNAR) to activate receptor-associated Janus kinase 1 (JAK1) and tyrosine kinase 2 (TYK2) kinases...
Alternative Titles
Full title
Regulation of type I interferon responses
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4084561
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4084561
Other Identifiers
ISSN
1474-1733
E-ISSN
1474-1741
DOI
10.1038/nri3581
