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The curative effect of fucoidan on visceral leishmaniasis is mediated by activation of MAP kinases t...

The curative effect of fucoidan on visceral leishmaniasis is mediated by activation of MAP kinases t...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4085487

The curative effect of fucoidan on visceral leishmaniasis is mediated by activation of MAP kinases through specific protein kinase C isoforms

About this item

Full title

The curative effect of fucoidan on visceral leishmaniasis is mediated by activation of MAP kinases through specific protein kinase C isoforms

Publisher

London: Nature Publishing Group UK

Journal title

Cellular & molecular immunology, 2014-05, Vol.11 (3), p.263-274

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Fucoidan can cure both antimony-sensitive and antimony-resistant visceral leishmaniasis through immune activation. However, the signaling events underlying this cellular response remain uncharacterized. The present study reveals that fucoidan induces activation of p38 and ERKI/2 and NF-κB DNA binding in both normal and Leishmania donovani.infected...

Alternative Titles

Full title

The curative effect of fucoidan on visceral leishmaniasis is mediated by activation of MAP kinases through specific protein kinase C isoforms

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4085487

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4085487

Other Identifiers

ISSN

1672-7681

E-ISSN

2042-0226

DOI

10.1038/cmi.2013.68

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