α1-antitrypsin increases interleukin-1 receptor antagonist production during pancreatic islet graft...
α1-antitrypsin increases interleukin-1 receptor antagonist production during pancreatic islet graft transplantation
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Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Although islet transplantation for individuals with type I diabetes has been shown to yield superior blood glucose control, it remains inadequate for long-term control. This is partly due to islet injuries and stresses that can lead to beta cell loss. Inhibition of excess IL-1β activity might minimize islet injuries, thus preserving function. The I...
Alternative Titles
Full title
α1-antitrypsin increases interleukin-1 receptor antagonist production during pancreatic islet graft transplantation
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4085519
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4085519
Other Identifiers
ISSN
1672-7681
E-ISSN
2042-0226
DOI
10.1038/cmi.2014.17
