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Host-cell sensors for Plasmodium activate innate immunity against liver-stage infection

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Host-cell sensors for Plasmodium activate innate immunity against liver-stage infection

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4096771

Host-cell sensors for Plasmodium activate innate immunity against liver-stage infection

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New York: Nature Publishing Group US

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After mosquito bite, the malaria parasite first infects the liver, where it is thought to be undetected by the host immune system as it develops into the blood-stage pathogen. Maria Mota and her colleagues now report that
Plasmodium
RNA is detected by hepatocytes, triggering an interferon response that controls the parasite burden in the live...

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Host-cell sensors for Plasmodium activate innate immunity against liver-stage infection

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Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4096771

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4096771

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ISSN

1078-8956

E-ISSN

1546-170X

DOI

10.1038/nm.3424

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