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Quantitative flux analysis reveals folate-dependent NADPH production

Quantitative flux analysis reveals folate-dependent NADPH production

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4104482

Quantitative flux analysis reveals folate-dependent NADPH production

About this item

Full title

Quantitative flux analysis reveals folate-dependent NADPH production

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2014-06, Vol.510 (7504), p.298-302

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

A metabolomics quantification of NADPH production and consumption fluxes in proliferating mammalian cells reveals that, in addition to canonical pathways such as the oxidative pentose phosphate pathway, NADPH can also be produced by a folate metabolism pathway, a discovery providing new insights into the metabolism of cell growth.
Folate generat...

Alternative Titles

Full title

Quantitative flux analysis reveals folate-dependent NADPH production

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4104482

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4104482

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature13236

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